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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAGE
All Species:
18.79
Human Site:
T412
Identified Species:
37.58
UniProt:
Q9UQ07
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ07
NP_055041.1
419
48014
T412
P
Q
Q
C
R
L
P
T
I
V
R
K
G
G
R
Chimpanzee
Pan troglodytes
XP_510176
419
47983
T412
P
Q
Q
C
R
L
P
T
I
A
R
K
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001112517
461
52662
T453
P
Q
Q
C
R
L
P
T
I
V
R
K
G
G
R
Dog
Lupus familis
XP_547985
458
51843
T450
P
K
Q
Y
H
L
P
T
I
E
R
K
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVS4
420
48046
T412
L
K
H
Y
H
L
P
T
I
N
R
K
G
G
E
Rat
Rattus norvegicus
Q62726
629
70550
S563
F
L
K
K
E
V
G
S
V
M
Q
R
V
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
Frog
Xenopus laevis
NP_001084801
411
47114
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786078
440
50923
S431
Y
G
H
F
Q
L
P
S
I
S
K
S
K
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
A435
R
P
W
M
A
V
S
A
P
F
Q
Q
S
H
Y
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
82.6
76.6
N.A.
83.5
27.8
N.A.
N.A.
28.6
63.2
N.A.
N.A.
26.7
N.A.
N.A.
50.6
Protein Similarity:
100
99.5
85.2
81.2
N.A.
89.5
42.4
N.A.
N.A.
43.9
73.2
N.A.
N.A.
42.7
N.A.
N.A.
68.4
P-Site Identity:
100
93.3
100
66.6
N.A.
53.3
0
N.A.
N.A.
0
0
N.A.
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
93.3
100
73.3
N.A.
60
46.6
N.A.
N.A.
0
0
N.A.
N.A.
0
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
28.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
9
% E
% Phe:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
0
0
0
0
42
42
9
% G
% His:
0
0
17
0
17
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
17
9
9
0
0
0
0
0
0
9
42
9
0
0
% K
% Leu:
9
9
0
0
0
50
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
34
9
0
0
0
0
50
0
9
0
0
0
0
0
0
% P
% Gln:
0
25
34
0
9
0
0
0
0
0
17
9
0
9
0
% Q
% Arg:
9
0
0
0
25
0
0
0
0
0
42
9
0
0
25
% R
% Ser:
0
0
0
0
0
0
9
17
0
9
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
17
0
0
9
17
0
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _